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Program

 

Sunday - July 15, 2018

16:00 - 19:00aaRegistration
    Research II - Conference desk in Foyer / Tea Room
17:00 - 21:00 Welcome -  Get Together 
    Research II - Tea Room
     

Monday - July 16, 2018

09:00 - 09:40 Opening with an overview of the topics
     
09:40 - 10:20 Michel Pleimling:
    An overview of the phenomenology of physical aging
10:20 - 10:50 Coffee break
10:50 - 11:30 Campell Gourlay:
    An Introduction to the actin cytoskeleton, its properties and its decline during ageing
11:30 - 12:10 Paolo  Sibani:
    Origin of common dynamical aspects in glassy materials and biological ecosystems: a qualitative discussion
12:10 - 14:20 Lunch break
14:20 - 14:40 CT - Jonas Rzezonka:
    Interaction Analysis of Longevity Interventions Using Survival Curves
14:40 - 15:20 Henrik J. Jensen:
    Aging as a consequence of evolutionary adaptation
15:20 - 15:50 Coffee break
15:50 - 16:30 Pieter Rein ten Wolde:
    Thermodynamics of Biochemical Copying
16:30 - 16:50 CT - Tailise C. de Souza G. Rodrigues
    Ageing, translation and noise - are they related?
16:50 - 17:30 Panel discussions
     
     

Tuesday - July 17, 2018

09:00 -09:40 Campell Gourlay:
    Killer Actin
09:40 -10:20 Pieter Rein ten Wolde:
    Theory on the optimal design of cell sensing systems
10:20 -10:50 Coffee break
10:50 -11:30 Paolo  Sibani:
    From micro- to macro: Record Dynamics as a coarse graining tool for aging systems
11:30 -12:10 Henrik Jeldtoft Jensen:
    Universal features of ageing through record dynamics
12:10 -12:30 CT - Darka Labavic:
    Dose-rate scaling laws in a generic cellular stress response model
12:30 -14:20 Lunch break
14:20 -15:00 Ala Trusina:
    Aging as stress response: examples from bacteria and higher eukaryotes
15:00 -15:40 Niek Welkenhuysen:
    Beyond asymmetry: the evolutionary advantages of an active damage retention mechanism
15:40 -16:10 Coffee break
16:10 -16:50 Dipanjan Roy:
    Spatiotemporal reorganization of brain rhythms on slow and fast time scales with healthy aging
16:50 -17:30 Nan Hao:
    Systems Biology of single-cell aging - Periodic silencing dynamics control cell aging
17:30 - 18:00 Panel discussions
     
     

Wednesday - July 18, 2018

09:00 -09:40 Juan P. Garrahan:
    Basics of slow relaxation, glasses and kinetically constrained dynamics
09:40 -10:20 Andre Barato:
    Cost and precision in stochastic thermodynamics
10:20 -10:50 Coffee break
10:50 -11:30 Michel Pleimling:
    Physical aging in materials: from vortex matter to skyrmion systems
11:30 -12:10 Nicholas E. Stroustrup:
    The temporal scaling of C.elegans’ aging
12:10 -12:30 Hildegard Meyer-Ortmanns:
    On the fate of dynamical systems under a trade-off between cost and
precision
12:30 -14:20 Lunch break
14:20 -15:00 Feng Liu:
    Induction of cellular senescence under various stress conditions
15:00 -15:40 Dipanjan Roy:
    Metastability, Causality and Synchronization in the aging brain: a new perspective
15:40 -16:30 Coffee break
     
16:40   Departure for the City tour at the porters / entree of the Jacobs University
17:30 -19:00 City tour
19:00 -22:00 Conference dinner
     

Thursday - July 19, 2018

09:00 -09:40 Jos Rohling:
    How the aging circadian clock affects our daily rhythms
09:40 -10:20 Sonja J. Prohaska:
    Running Histone Code on a Chromatin Computer 
10:20 -10:50 Coffee break
10:50 -11:30 Gasper Tkačik:
    Information processing in neural and gene regulatory networks
11:30 -11:50 Juan P. Garrahan:
    Fluctuation properties of counting observables and their first passage times in stochastic systems 
11:50 -12:10 CT - Philipp Fleig:
    Task-specific adaptation of a living flow network
12:10 -14:20 Lunch break
14:20 -15:00 Katarzyna Macieszczak:
    Unified thermodynamic uncertainty relations in linear response
15:00 -15:20 CT - Xavier Viader-Godoy:
    Length dependence of the elastic properties and secondary structure of single- stranded D N A
15:20 -15:50 Coffee break
15:50 -16:30 Sebastian Goldt:
    Stochastic thermodynamics of learning
16:30 -17:10 Felix Ritort:
    Experimental measurement of information-content in non-equilibrium systems
17:10 - 17:30 Panel discussions
     
     

Friday - July 20, 2018

09:00 -09:40 Gasper Tkačik:
    Intrinsic limits to gene regulation by global crosstalk
09:40 -10:20 Sonja J. Prohaska:
    Epigenetics: Regulation of a Special Kind
10:20 -10:50 Coffee break
10:50 -11:30 Felix Ritort:
    Q-stat thermodynamics: a new perspective on non-equilibrium phenomena
11:30 -11:50 CT - Marta Gironella:
    Relaxational kinetics in red blood cell mechanics: linking physical to biological aging
11:50 -12:30 Closure
12:30 -14:00 Lunch  / Departure

CT= Contributed Talk


 
Talks ordered with respect to six subtopics:
1. Aging of matter and materials
2. Aging on the individual and collective level: from bacteria to ecological systems
3. Aging of the human brain from the perspective of neuroscience and nonlinear dynamics
4. Genetic basis of lifespan and longevity: Aging on the genetic and cellular level
5. Biological processes as error-prone processing of information
6. Trade-off between costs, speed and precision in biological networks

 



1. Aging of matter and materials

  • An overview of the phenomenology of physical aging (Michel Pleimling, Blacksburg)
  • Physical aging in materials: from vortex matter to skyrmion systems (Michel Pleimling, Blacksburg)
  • Basics of slow relaxation, glasses and kinetically constrained dynamics (Juan P. Garrahan, Nottingham)
  • From micro-to macro: record dynamics as a coarse graining tool for aging systems (Paolo Sibani, Odense)
  • Origin of common dynamical aspects in glassy materials and biological ecosystems: a qualitative discussion (Paolo Sibani, Odense)
  • CT: Relaxational kinetics in red blood cell mechanics: linking physical to biological aging (Marta Gironella, Barcelona)
  • CT: Length dependence of the elastic properties and secondary structure of single- stranded DNA (Xavier Viader-Godoy, Barcelona)

2. Aging on the individual and collective level: from bacteria to ecological systems

  • Aging as stress response: examples from bacteria and higher eukaryotes (Ala Trusina, Copenhagen)
  • How the aging circadian clock affects our daily rhythms (Jos H.T. Rohling, Leiden)
  • Ageing as a consequence of evolutionary adaptation (Henrik J. Jensen, London)
  • Universal features of ageing through record dynamics (Henrik J. Jensen, London)
  • From micro-to macro: record dynamics as a coarse graining tool for aging systems  (Paolo Sibani, Odense)
  • CT: Interaction analysis of longevity interventions using survival curves (Jonas Rzezonka, Köln)
  • CT: Beyond asymmetry: the evolutionary advantages of an active damage retention mechanism (Niek Welkenhuysen, Gothenburg)
  • CT: Task-specific adaptation of a living flow network (Philipp Fleig, Göttingen)

3. Aging of the human brain from the perspective of neuroscience

  • Spatiotemporal reorganization of brain rhythms on slow and fast time scales with healthy aging (Dipanjan Roy, Manesar)
  • Metastability, causality and synchronization in the aging brain: a new perspective (Dipanjan Roy, Manesar)

4. Genetic basis of lifespan and longevity: Aging on the genetic and cellular level

  • An Introduction to the actin cytoskeleton, its properties and its decline during ageing (Campbell W. Gourlay, Canterbury)
  • Killer Actin (Campbell W. Gourlay, Canterbury)
  • The temporal scaling of C.elegans’ aging (Nicolas Stroustrup, Barcelona)
  • Induction of cellular senescence under various stress conditions (Feng Liu, Nanjing)
  • Systems biology of single-cell aging - periodic silencing dynamics control cell aging (Nan Hao, San Diego)
  • CT: Ageing, translation and noise - are they related? (Tailise C. de Souza Guerreiro, Warwick)
  • CT: Dose-rate scaling laws in a generic cellular stress response model (Darka Labavic, Lille)

5. Biological processes as error-prone processing of information

  • Information processing in neural and gene regulatory networks (Gasper Tkacik, Klosterneuburg)
  • Intrinsic limits to gene regulation by global crosstalk (Gasper Tkacik, Klosterneuburg)
  • Running Histone Code on a Chromatin Computer  (Sonja Prohaska, Leipzig)
  • Epigenetics: Regulation of a Special Kind  (Sonja Prohaska, Leipzig)

6. Trade-off between costs, speed and precision in biological networks

  • Cost and precision in stochastic thermodynamics (Andre Barato, Dresden)
  • Stochastic thermodynamics of learning (Sebastian Goldt, Paris)
  • Unified thermodynamic uncertainty relations in linear response (Katarzyna Macieszczak, Cambridge)
  • Experimental measurement of information-content in non-equilibrium systems (Felix Ritort, Barcelona)
  • Fluctuation properties of counting observables and their first passage times in stochastic systems (Juan P. Garrahan, Nottingham)
  • Q-stat thermodynamics: a new perspective on non-equilibrium phenomena (Felix Ritort, Barcelona)
  • Thermodynamics of biochemical copying (Pieter Ren ten Wolde, Amsterdam)
  • Theory on the optimal design of cell sensing systems (Pieter Ren ten Wolde, Amsterdam)
  • On the performance of dynamical systems under a trade-off between cost and precision (Hildegard Meyer-Ortmanns, Bremen)